Neurobio Exam 1

14 Responses | Created by ebrinza |
  1. 1

    In MS, only axons of the CNS are affected, while conduction velocity of peripheral sensory and motor axons is normal. What glial cell is affected?

  2. 2

    You find that the conduction velocity of squid axon with a diameter of 900 µm is 50 m/sec. What is the expected conduction velocity of an axon from a squid axon that has a diameter of 225 µm?

  3. 3

    At resting potential what is happening in the neuron?

  4. 4

    As the action potential is halfway through the falling phase, what is happening in the neuron?

  5. 5

    When sodium is flowing into the cell it is defined as:

  6. 6

    In terms of permeability at rest, PK is ____, and PNa is ______.

  7. 7

    This period determines the maximum frequency with which a neuron can fire action potentials.

  8. 8

    In the presence of this toxin, the cell constantly spikes

  9. 9

    This toxin is responsible for blocking potassium voltage-gated channels, except the delayed rectifier.

  10. 10

    You can increase propogation velocity by _______ the diameter, or ______ the membrane capacitance.

  11. 11

    24. This autosomal dominant disorder starts in childhood with episodic burning and pain in the feet and lower legs, provoked by exercise.

  12. 12

    What is the gx of a cell at equilibrium potential, when there is no net movement across the cell membrane.

  13. 13

    At resting potential, which is higher?

  14. 14

    You record the responses of a neuron to two depolarizing stimuli. Stimulus 1 barely exceeds threshold and stimulus 2 is greater than stimulus 1. Are the neuron's responses same or different?

  15. 15

    In an unidentified animal cell, ion “A” has a greater permeability than ion “B”. What happens to Vm if the cell is permeable only to ion “B”?

  16. 16

    You inject positive current into a toad axon and measure a 0.77 mV depolarization at a distance 2λ away. What was the amplitude of depolarization at your injection site?

  17. 17

    Which toxin that could be used to label channels highly concentrated in the nodes of Ranvier?

  18. 18

    How does myelin affect gi?

  19. 19

    How does myelin affect gm?

  20. 20

    The voltage-gated socium channels consists of ___ distinct domains.

  21. 21

    Each domain of the voltage-gated sodium channels has ___ transmembrane segments.

  22. 22

    On voltage-gated potassium channels, ___ is the voltage sensor.

  23. 23

    The overshoot at the end of an action potential is caused by the slow kinetics of which voltage-gated channel?

  24. 24

    The discovery of the sodium and potassium voltage-gated channels was discovered by which experimental method?

  25. 25

    Which of the following plays a role in the resting potential of a cell?

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